Having used the Boyle's bottle vaporizer apparatus out of necessity in
a developing country, the concentration of agent that had been admini
stered was investigated retrospectively. Three anaesthetic agents, hal
othane, isoflurane and enflurane, were measured at different temperatu
res, using a Boyle's anaesthetic machine and a Boyle's bottle in circu
it with a Magill breathing system connected to a Rascal II Agent Monit
or. Bubbling a fresh gas flow of 51.min(-1) through the anaesthetic li
quids generated concentrations in excess of 12%. Elevating the initial
temperature of the vaporizer increased the delivered concentration, a
lthough this effect was short-lived. Therapeutic concentrations of vap
our were achieved for all three agents by avoiding bubbling and manipu
lating the 'splitting ratio' lever. The Boyle's bottle vaporizer may b
e used with modern anaesthetic agents such as halothane, isoflurane an
d enflurane. However, the limitations of and variations between vapori
zers should be borne in mind. An agent monitor employed at the patient
end of the circuit would be an important safety feature.