Background. Tuberculous involvement of the esophagus has been extremel
y rare during the past 40 years. It will be, however, more frequently
encountered in the future, as the number of immunocompromised patients
is growing. This condition is usually secondary to infection in other
thoracic sites, such as lungs, larynx, or mediastinum. The diagnosis
is difficult if the suspicion of tuberculosis is not raised. Dysphagia
and cough after ingestion of fluids and food are common symptoms with
out any other specific signs in these patients. Diagnosis is based on
combination of esophagography, esophagoscopy, bronchoscopy, and comput
ed tomographic scan. Methods. We present 3 patients with tuberculous f
istulas of the esophagus. Two of our 3 patients were treated successfu
lly with the combination of operation and antituberculous chemotherapy
. Fistulas were resected and closed directly. Suture lines were secure
d with pedicled pleural naps. Results. Both patients who underwent ope
ration recovered without complications. One patient died without defin
itive diagnosis and treatment. Conclusions. Treatment of tuberculous f
istulas consists of operation and antituberculous chemotherapy, althou
gh antituberculous medication alone has been suggested to be effective
if the diagnosis is early. However, operation is usually necessary to
establish the correct diagnosis. Therefore, we believe that if the ca
use of the esophageal fistula cannot be verified, thoracotomy should b
e performed. If the fistula is left untreated the consequences are usu
ally fatal.