While most ocular infections are benign, others can be associated with
devastating Visual consequences. Most patients present with either oc
ular discharge, visual symptoms or a red or painful eye. The primary c
are physician is usually the ill-st to evaluate these patients. We hav
e separated ocular infections into 3 groups. Infections affecting the
cornea and conjunctiva often present with eye pain and a red eye; noni
nfectious aetiologies can have a similar presentation. Infections insi
de the eye (endophthalmitis) often have devastating consequences. They
usually occur following penetrating ocular trauma or after intraocula
r surgery. Prompt referral to an ophthalmologist is crucial. Infection
s in the soft tissue surrounding the eye (ocular adnexa and orbit) can
involve the eye indirectly and can spread from the orbit into the bra
in, The purpose of this article is to review ocular infections and cur
rent opinion regarding treatment. A general guideline should be that t
he approach to treatment be governed by the severity of symptoms and t
he magnitude of possible consequences. Mild external infections can be
typically treated empirically. Severe conjunctivitis, and any corneal
infection, require aggressive management, often including cultures an
d broad spectrum antibiotics; cultures are often used to guide treatme
nt. Devastating vision loss can occur, even with aggressive management
. Preseptal cellulitis in adults and older children can be managed con
servatively with oral antibiotics if the orbit and optic nerve are not
involved and the patient is otherwise healthy. Orbital or optic nerve
involvement, on the other hand, demands orbital imaging and more aggr
essive intervention. Patients who have had recent surgery are at risk
for developing endophthalmitis. Complaints of pain or a red eye must b
e taken very seriously. These patients must be considered to have an i
ntraocular infection until it can be ruled out, and should be aggressi
vely managed by a physician trained in eye diseases and surgery.