CHIRAL PHOSPHINE OXIDES AND CHIRAL ESTERS IN STEREOSELECTIVE INTERMOLECULAR ACYLATION REACTIONS OF PHOSPHINE OXIDES

Authors
CAVALLA D GUEGUEN C NELSON A OBRIEN P RUSSELL MG WARREN S
Citation
D. Cavalla et al., CHIRAL PHOSPHINE OXIDES AND CHIRAL ESTERS IN STEREOSELECTIVE INTERMOLECULAR ACYLATION REACTIONS OF PHOSPHINE OXIDES, Tetrahedron letters, 37(41), 1996, pp. 7465-7468
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
41
Year of publication
1996
Pages
7465 - 7468
Database
ISI
SICI code
0040-4039(1996)37:41<7465:CPOACE>2.0.ZU;2-4
Abstract
Single diastereomers of beta-keto phosphine oxides have been generated from intermolecular acylation of phosphine oxides using either chiral esters or chiral phoshine oxides. In most cases, reduction of the ket one products was not affected by the presence of extra chiral centres. Some mechanistic points of interest in the acylation reactions are di scussed. Copyright (C) 1996 Elsevier Science Ltd