OLIGONUCLEOTIDES CONTAINING 2'-DEOXYISOGUANOSINE OR 7-DEAZA-2'-DEOXYISOGUANOSINE - BASE-PAIRING AND AGGREGATION

Authors
Citation
F. Seela et Cf. Wei, OLIGONUCLEOTIDES CONTAINING 2'-DEOXYISOGUANOSINE OR 7-DEAZA-2'-DEOXYISOGUANOSINE - BASE-PAIRING AND AGGREGATION, Collection of Czechoslovak Chemical Communications, 61, 1996, pp. 114-115
Citations number
3
Categorie Soggetti
Chemistry
ISSN journal
00100765
Volume
61
Year of publication
1996
Pages
114 - 115
Database
ISI
SICI code
0010-0765(1996)61:<114:OC2O7>2.0.ZU;2-R
Abstract
Oligonucleotides containing 2'-deoxyisoguanosine (iG(d)) or 7-deaza-2' -deoxyiso-guanosine (c(7)iG(d)) were synthesized using the phosphonate s or phosphoramidites 1-6. Parallel-stranded duplexes are formed when iG(d) or c(7)1G(d) base pairs with dC. The oligonucleotide 5'd(T-4-iG( 4)-T-4) forms an aggregate with a defined structure.