J. Fruhwirth et al., PREOPERATIVE EMBOLIZATION OF CAROTID-BODY TUMORS - A METHOD FOR INCREASING TUMOR OPERABILITY, HNO. Hals-, Nasen-, Ohrenarzte, 44(9), 1996, pp. 510-513
During surgical resections carotid body tumors may bleed profusely due
to their vascularity. Preoperative angiographic embolization of tumor
-supplying arteries has reduced intraoperative blood loss significantl
y. The present study reviews our clinical experiences with 13 paragang
liomas of the carotid bifurcation in 12 patients during the past 5 yea
rs. In 6 patients (46.1%) computed tomography and magnetic resonance i
maging demonstrated extensive spread of the tumor up to the base of th
e skull. Tumors of this size were initially assessed as being inoperab
le but curative surgical resections were performed after embolization
of tumor-supplying arteries by intravascular injections of Gelfoam and
implantations of microcoils. Vascular reconstruction of the internal
carotid artery by a saphenous vein graft was required in 4 patients (3
0.7%). In 3 malignant paragangliomas (23.0%) adjuvant radiotherapy of
50-60 Gy was administered to the tumor site after surgery. During an a
verage follow-up of 29 months, one malignant paraganglioma was found t
o have recurred locally 13 months after initial therapy.