Wr. True et al., MODELS OF TREATMENT SEEKING FOR ALCOHOLISM - THE ROLE OF GENES AND ENVIRONMENT, Alcoholism, clinical and experimental research, 20(9), 1996, pp. 1577-1581
We investigated the relative influence of genes and environment on the
decision to seek treatment for alcoholism under three models of healt
h care utilization. Lifetime alcohol dependence and two measures of tr
eatment seeking for alcohol problems were determined from a 1992 telep
hone administration of the Diagnostic Interview Schedule. Data were an
alyzed from 1,864 monozygotic and 1,492 dizygotic male twin respondent
s from the Vietnam Era Twin Registry. Genetic and environmental contri
butions to the decision to seek treatment for alcoholism were assessed
under competing models for the relationship between genetic influence
s on alcoholism risk and genetic influences on treatment seeking among
those who became alcoholics. Under the best-fitting model, genetic in
fluence accounted for 41% of the variance in treatment seeking and 55%
of the liability for alcoholism. Shared environment explained none of
the variance in liability for alcoholism, but 40% of the variance in
treatment seeking. The severity of alcoholism alone is an inadequate m
odel of treatment seeking, because decisions to seek alcohol treatment
are also influenced by substantial genetic and or shared environmenta
l factors unrelated to the determinants of alcoholism.