Background: Surgical treatment for severe obesity is sometimes recomme
nded. Many long-term risks, particularly to adolescents and to subsequ
ent pregnancies, are still being determined. Case: A 23-year-old woman
, gravida 6, para 2, treated for morbid obesity during adolescence wit
h gastric bypass surgery, presented at 6 weeks' gestation with severe
microcytic anemia. Significant iron and cobalamin deficiencies were fo
und. Although the vitamin B-12 deficiency responded to parenteral trea
tment, the iron deficiency was refractory to oral supplementation beca
use of malabsorption. By 30 weeks' gestation, the patient required blo
od transfusions to correct the progressive anemia. Subsequently, she d
elivered a healthy male infant at term. Conclusion: Severe iron defici
ency anemia resulting from malabsorption can complicate pregnancy foll
owing gastric bypass surgery for morbid obesity. For women of childbea
ring age, this potential adverse effect must be considered.