Background: Before the advent of antibiotic therapy, Salmonella typhi
infection during pregnancy was associated with a high incidence of fet
al and neonatal death. Little information is available about the risk
to the fetus or the newborn of a pregnant woman infected by non-typhoi
d salmonella, and treatment recommendations do not exist. Case: We rep
ort a case of transplacental infection of a fetus by non-typhoid salmo
nella in a woman with gastroenteritis. Salmonella enteritidis was cult
ured from stool of the pregnant woman, who had diarrhea and fever befo
re cesarean was performed at 29 weeks' gestation. The premature girl d
ied 4 hours after birth from septic shock. Salmonella enteritidis was
cultured from blood cultures and swabs of the premature infant and fro
m the placenta and uterus. Conclusion: This observation argues in favo
r of antibiotic treatment for non-typhoid salmonella infection in preg
nancy because of the risk of transplacental infection of the fetus.