Objective: To determine the influence of back extensor strength on ver
tebral fractures in 36 women with osteoporosis. Design: We conducted a
cross-sectional study of female patients with osteoporosis by assessi
ng anthropometric variables, bone mineral density, muscle strength, le
vel of physical activity, and radiographic findings in the spine. Mate
rial and Methods: The 36 study subjects with osteoporosis, who ranged
from 47 to 84 years of age, satisfied specific inclusion and exclusion
criteria that minimized confounding factors related to pathophysiolog
ic features, diet, and medications, A physical activity score was dete
rmined for each subject on the basis of daily physical activities rela
ting to homemaking, occupation, and sports. Results: The range of the
physical activity scores-from 2 to 13-indicated that no subject was in
volved in unusually demanding physical activities, Bone mineral densit
y values ranged from 0.49 to 0.92 g/cm(2), Thoracic kyphosis ranged fr
om 31.0 to 84.0 degrees, Isometric strength of the back extensor muscl
es ranged from 7.3 to 34.0 kg, Statistical analysis demonstrated a sig
nificant negative correlation between the strength of the back extenso
r muscles and thoracic kyphosis, Significant negative correlations wer
e also found between back extensor strength and the number of vertebra
l compression fractures and between bone mineral density and the numbe
r of vertebral fractures. Conclusion: The negative association between
back extensor strength and both kyphosis and number of vertebral frac
tures suggests that increasing back strength may prove to be an effect
ive therapeutic intervention for the osteoporotic spine, In persons wi
th stronger back muscles, the risk of vertebral fractures will likely
decrease.