An unacceptably high incidence of preterm labour is seen in the black
and coloured communities of South Africa. This hypothesis proposes tha
t sodium-potassium adenosine triphosphatase activity plays an importan
t role in preterm labour, The impaired activity of the sodium pump lea
ds to increased cytosolic calcium levels, which may trigger contractio
n of myometrial smooth-muscle cells, resulting in preterm labour.