OSTEOSARCOMA METASTATIC TO THE OVARY - A CASE-REPORT AND REVIEW OF THE LITERATURE

A 23-year-old black woman presented with abdominal pain of sudden onse t, high fever, chills, and an elevated serum alkaline phosphatase leve l. Examination revealed a tender abdominopelvic mass consistent with a n ovarian mass. Her medical history was significant for an osteosarcom a of the left humerus removed 7 rears earlier and excision of multiple pulmonary and chest wall metastases 7 years earlier. Exploratory lapa rotomy revealed a solid hemorrhagic left ovarian mass and ascites. The re was no other evidence of disease. A left salpingo-oophorectomy was performed. Pathological examination of the mass showed metastatic oste osarcoma. Four months later, the patient died of widespread osteosarco ma. The clinicopathologic features of ovarian osteogenic sarcomas repo rted in the literature ale reviewed. Pain, fever, and elevated serum a lkaline phosphatase levels may be the presenting clinical features of this rare ovarian tumor.