STRATEGY OF PRESENT-DAY THERAPY OF PH-POS ITIVE CHRONIC MYELOID-LEUKEMIA

Authors
KHOROSHKO ND TURKINA AG ZHURAVLEV VS SOKOLOVA MA MIKHAILOVA IN ZAKHAROVA AV DOMRACHEVA EV SEMENOVA EA
Citation
Nd. Khoroshko et al., STRATEGY OF PRESENT-DAY THERAPY OF PH-POS ITIVE CHRONIC MYELOID-LEUKEMIA, Terapevticeskij arhiv, 68(7), 1996, pp. 22-27
Citations number
16
Categorie Soggetti
Medicine, General & Internal
Journal title
Terapevticeskij arhiv → ACNP
ISSN journal
00403660
Volume
68
Issue
7
Year of publication
1996
Pages
22 - 27
Database
ISI
SICI code
0040-3660(1996)68:7<22:SOPTOP>2.0.ZU;2-G
Abstract
The aim of this paper was to show the validity of programmed treatment of chronic myeloid leukemia (CML) patients regarding the risk group. In a group of low CML risk monochemotherapy (myelosan or hydroxyurea) was applied. In a group of moderate or high CML risk cytostatic therap y was performed in two variants. as monotherapy and polychemotherapy. Of 112 patients with CML, 50 received cytostatics plus long-term cours e of interferon-alpha. The combined treatment was well tolerated.