Concerning the soft tissue reaction to stainless steel (316L) fibre me
sh structures, it was found that mesh materials composed of small diam
eter fibres (2-8 mu m) were lined by several layers of macrophages and
giant cells. In addition, the majority of these mesh implants were fi
lled with inflammatory cells. In contrast, mesh materials with a large
r fibre diameter (12-22 mu m) evoked less or no inflammatory reaction.
An explanation for this observation could be the occurrence of shear
displacements at the soft tissue-implant interface. In addition, corro
sion phenomena as a result of the increased surface area of small fibr
e diameter meshes can be responsible for a greater toxic ion release.
In this study the corrosion rates and the influence of shear stress on
the corrosion rates of different stainless steel 316L fibre mesh stru
ctures were compared under in vitro laboratory conditions. It appeared
that the effect of mechanical stress on 316L corrosion was a signific
ant increase in the concentration of corrosion products in the loaded
situation. Furthermore, the effect of fibre diameter on the release of
corrosion products was a significant difference in ion release betwee
n mesh materials made of fibres with a diameter of 4 mu m compared to
meshes with a diameter of 12 and 22 mu m. Therefore it was concluded t
hat the chemical properties of fibre mesh implant material, together w
ith the ability to release toxic ions, are an important determinant in
the final tissue behaviour.