A novel line scan diffusion imaging sequence (LSDI) is introduced. LSD
I is inherently insensitive to motion artifacts and high quality diffu
sion maps of the brain can be obtained rapidly without the use of head
restraints or cardiac gating, Results from a stroke study and abdomin
al diffusion images are presented. The results indicate that it is fea
sible to use the LSDI technique for clinical evaluation of acute ische
mic stroke, In contrast to echo-planar diffusion imaging, LSDI does no
t require modified gradient hardware and can be implemented on convent
ional scanners. Thus, LSDI should dramatically increase the general av
ailability of robust clinical diffusion imaging.