Tg. Voznesenskaya et al., PSYCHOPHYSIOLOGICAL ASPECTS OF OBESITY TR EATMENT BY ISOLIPAN, Zurnal nevropatologii i psihiatrii im. S.S. Korsakova, 96(4), 1996, pp. 59-62
20 patients with obesity were examined. Their weight was Increased as
compared with Ideal values by 30-140%. The patients were characterized
by anxious or depressive disturbances (Spilberg's and Beck tests) and
alterations of alimentary behaviour in form of prevalence of emotiona
l and external alimentary behaviour (EMAB and EAB, respectively). The
study of cognitive negative variations (CNV) revealed the decrease of
late wave's area, which correlated reversely with levels of anxiety, d
epression and EMAB expression. The Isolipan administration (15 mg, 2 t
imes/daily during 3 months) together with hypocaloric diet resulted in
average weight loss equal to 12,3 kg in the whole group. These change
s correlated well with normalization of both alimentary behaviour (In
the form of decrease of EMAB and EAB indices) and emotional state, and
increase of decreased late CNV with disappearance of pathological psy
cho-physiological correlations between CNV and emotional state.