BETA-ALANINE BINDS TO UPTAKE SITES WHEN USING PHYSIOLOGICAL CONCENTRATIONS OF SODIUM

Authors
FERNANDEZ I
Citation
I. Fernandez, BETA-ALANINE BINDS TO UPTAKE SITES WHEN USING PHYSIOLOGICAL CONCENTRATIONS OF SODIUM, Medical science research, 24(9), 1996, pp. 601-602
Citations number
10
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Medical science research → ACNP
ISSN journal
02698951
Volume
24
Issue
9
Year of publication
1996
Pages
601 - 602
Database
ISI
SICI code
0269-8951(1996)24:9<601:BBTUSW>2.0.ZU;2-G
Abstract
H-3-beta-Alanine binding was studied in Krebs-Ringer bicarbonate-buffe red (KRB) medium, or the same medium made Na+-free (KRB-Na+). Even at low H-3-beta-alanine concentration, binding in the presence of sodium was inhibited by the beta-alanine uptake inhibitor arecaidine and by s trychnine. The results indicate that beta-alanine binds to uptake site s when using media with physiological concentrations of sodium.