PARTIAL LIPODYSTROPHY ASSOCIATED WITH JUVENILE DERMATOMYOSITIS - REPORT OF 2 CASES

Citation
E. Quecedo et al., PARTIAL LIPODYSTROPHY ASSOCIATED WITH JUVENILE DERMATOMYOSITIS - REPORT OF 2 CASES, Pediatric dermatology, 13(6), 1996, pp. 477-482
Citations number
31
Categorie Soggetti
Dermatology & Venereal Diseases",Pediatrics
Journal title
ISSN journal
07368046
Volume
13
Issue
6
Year of publication
1996
Pages
477 - 482
Database
ISI
SICI code
0736-8046(1996)13:6<477:PLAWJD>2.0.ZU;2-0
Abstract
A 27-year-old woman and a 13-year-old girl diagnosed with juvenile der matomyositis in childhood developed clinical findings of partial lipod ystrophy 10 years after diagnosis. Exhaustive clinical and laboratory examinations showed an association with other abnormalities: hypertric hosis, steatohepatitis, and an abnormal insulin response to the glucos e loading test in the first patient. Hypertrichosis, steatohepatitis, insulin-resistant diabetes mellitus, and acanthosis nigricans were obs erved in the second patient. Renal function was normal in both patient s. Although a localized form of lipodystrophy has been reported associ ated with connective tissue disease (connective tissue lipoatrophy), t he partial form has been infrequently described in association with ju venile dermatomyositis.