BARTTERS-SYNDROME - RENAL SCINTIGRAPHIC APPEARANCE AFTER CAPTOPRIL ADMINISTRATION

We report a case of Bartter's syndrome, a rare disease characterized b y hypokalemia, increased plasma renin and angiotensin II levels with n ormal blood pressure, During the diagnostic work-up, the patient had r enal scintigraphy in baseline and after captopril administration, Phar macological blockade of the renin-angiotensin system with captopril re sulted in bilateral and symmetrical renal abnormalities (increase of p arenchymal transit time, time to maximum activity and retained cortica l activity, with cortical trapping of the radiopharmaceutical). Baseli ne scintigraphy was normal, The findings are consistent with Bartter's syndrome pathogenesis, Captopril renography may be useful to differen tiate Bartter's syndrome from other covert causes of hypokalemia.