CATALYTIC ENANTIOSELECTIVE OXIDATION OF SULFIDES WITH A CHIRAL TITANIUM COMPLEX

Authors
BRUNEL JM KAGAN HB
Citation
Jm. Brunel et Hb. Kagan, CATALYTIC ENANTIOSELECTIVE OXIDATION OF SULFIDES WITH A CHIRAL TITANIUM COMPLEX, Bulletin de la Societe chimique de France, 133(11), 1996, pp. 1109-1115
Citations number
60
Categorie Soggetti
Chemistry Inorganic & Nuclear",Biology,Chemistry
Journal title
Bulletin de la Societe chimique de France → ACNP
ISSN journal
00378968
Volume
133
Issue
11
Year of publication
1996
Pages
1109 - 1115
Database
ISI
SICI code
0037-8968(1996)133:11<1109:CEOOSW>2.0.ZU;2-5
Abstract
A catalytic asymmetric oxidation of sulfides by cumyl hydroperoxide in the presence of a chiral titanium catalyst is reported. The influence of the nature of the titanium alkoxide and the role of 2-propanol on the enantioselectivity have also been investigated. The most efficient catalyst has been defined as a combination Ti(Oi-Pr)(4)/(R,R)-(DET)/i -PrOH, 1:4:4, in the presence of 4 Angstrom molecular sieves. Asymmetr ic oxidation of various sulfides has been achieved in enantiomeric exc esses up to 96%.