AUGER-ELECTRON SPECTRA OF RADIONUCLIDES FOR THERAPY AND DIAGNOSTICS

The present paper documents the calculation of radiation spectra and o f radial dose distribution around a point source for 24 selected radio nculides. The radionculides were ordered into three groups: Nuclides p otentially useful for therapy by emission of Auger electrons: Cr-51, C u-64, Ga-67, Se-73, Se-75, Br-77, Br-80, Tc-94, Tc-99m, In-114m, In-11 5m, I-123, I-124, I-125, Tm-167, Pt-193m, and Pt-195m, nuclides potent ially useful for therapy by alpha-particles with additional emission o f Auger electrons: Bi-212, At-211 and Fm-255, and nuclides potentially useful for electron Auger-therapy with simultaneous PET diagnosis: Se -73, Tc-94 and I-124. The calculations imply strongly the development of labelled DNA-seeking compounds useful as carrier for the Auger- and Coster-Kronig electron-emitting radionuclides.