Kk. Singh et Gj. Jha, EFFECT OF CHRONIC FENVALERATE (SYNTHETIC PYRETHROID) INTOXICATION ON THE IMMUNE-RESPONSE OF GOATS TO BRUCELLA-ABORTUS STRAIN-19 VACCINE, Journal of Comparative Pathology, 115(3), 1996, pp. 299-303
Fenvalerate, a widely used pesticide, was administered orally to goats
at a dose rate of 15 mg/kg body weight, daily for 270 days. After 90
days of dosing, the animals, together with appropriate controls, were
vaccinated with Brucella abortus strain 19. The fenvalerate reduced bo
th the humoral and cell-mediated immune responses, as assessed by the
standard tube agglutination test and delayed hypersensitivity test, re
spectively. (C) 1996 W.B. Saunders Company Limited