SEMIEMPIRICAL MODELING OF PROTEIN SPATIAL STRUCTURE WITH TRITIUM PLANIGRAPHY

Authors
BOGACHEVA EN MOROZ AP SHISHKOV AV BARATOVA LA
Citation
En. Bogacheva et al., SEMIEMPIRICAL MODELING OF PROTEIN SPATIAL STRUCTURE WITH TRITIUM PLANIGRAPHY, Molecular biology, 30(3), 1996, pp. 379-384
Citations number
35
Categorie Soggetti
Biology
Journal title
Molecular biology → ACNP
ISSN journal
00268933
Volume
30
Issue
3
Year of publication
1996
Part
2
Pages
379 - 384
Database
ISI
SICI code
0026-8933(1996)30:3<379:SMOPSS>2.0.ZU;2-2
Abstract
An algorithm is proposed for modeling the 3D structure of globular pro teins, including secondary structure prediction from primary structure , determination of contacts from tritium accessibility (tritium planig raphy), and sequential element packing from the amino to the carboxy e nd with account for contact regions and connection length. With sperm whale myoglobin, it is shown that the approach yields a realistic mode l.