Objective: This study sought to evaluate maternal characteristics and
pregnancy outcomes among women with hyperemesis gravidarum. Methods: W
e performed a retrospective analysis of pregnancy records of obstetric
admissions during a 6-year period. Women treated as out-patients for
hyperemesis were also identified. Hyperemesis was defined as excessive
nausea and vomiting resulting in dehydration, extensive medical thera
py, and/or hospital admission. Statistical analysis was by t-test and
chi square. Results: We identified 193 women (1.5%) who developed hype
remesis among 13053 women. Racial status, marital status, age, and gra
vidity were similar between the hyperemesis patients and the general p
opulation. However, there were less women with hyperemesis who were pa
ra 3 or greater. Forty-six women (24%) required hospitalization for hy
peremesis, mean hospital stay 1.8 days, range 1-10 days. One patient r
equired parenteral nutrition, two had yeast esophagitis, none had HIV
infection, psychiatric pathology or thyroid disease. Pregnancy outcome
s between hyperemesis patients and the general population were similar
for mean birth weight, mean gestational age, deliveries less than 37
weeks, Apgar scores, perinatal mortality or incidence of fetal anomali
es. Our incidence of hyperemesis (1.5%) is similar to that of other pu
blished reports. Conclusion: Women with hyperemesis have similar demog
raphic characteristics to the general obstetric population, and have s
imilar obstetric outcomes. Copyright (C) 1996 International Federation
of Gynecology and Obstetrics.