THE TREATMENT OF TENSION-TYPE HEADACHE AN D OF VEGETATIVE CRISES BY LERIVON ADMINISTRATION

20 patients with vegetative crises (panic attacks) and 20 patients wit h tension-type headache were treated by Lerivon (tetracyclic antidepre ssant) administration. The folloving parameters were Investigated: the degree of headache expression according to visual analogous scale, th e vegetative crises frequency and depression gravity by means of Spilb erg test, the depression intensity by means of Back scale. The areas o f different components of contingent negative deviation (CND)-early, l ate, postimperative negative waves as well as total CND area-were exam ined either. Both high clinical effecty of the preparation and normali sation of psychophysiological parameters were found. 30 mg was the com mon daily dose for the patients with psychophisiological disorders. Th e clinical effect was observed quickly (7-10 days). The patients toler ated drug administration well, the sleepiness was the only side-effect . Thus, Lerivon proved highly effective for the treatment of both psyc hovegetative and algesic disorders and had some advantages as compared with commonly used tricyclic antidepressants.