MAGNETOENCEPHALOGRAPHICAL ANALYSIS OF FOCAL CORTICAL HETEROTOPIA

Focal cortical heterotopia is often associated with intractable seizur es, Recent papers have reported that magnetic resonance imaging (MRI) demonstrates cortical heterotopia well compared with other imaging mod alities, e.g. computed tomography scan. The authors analyzed the local ization of epileptic spike foci of focal cortical heterotopia by 37 ch annel magnetoencephalography (MEG), and superimposed these dipoles on MRI. The estimated dipoles were observed to be located in a limited ar ea, which corresponded to a focal cotical heterotopia on MRI. The pres ent paper demonstrates that the combination of MEG and MRI is very adv antageous for determination of the three dimensional localization of e pileptic foci in patients with focal cortical heterotopia.