Many physicians have inadequate Knowledge of the science of medical de
cision making and the health care system. We tested the impact of a me
dical school course in Clinical Epidemiology, and Health Services Deli
very using a prospective cohort design with participants from two clas
ses. A 15 item pre-test was given to second-year students followed by
the course which covered clinical and classical epidemiology, research
methodology, biostatistics and health services delivery. The question
s were embedded in the final examination and were also administered to
a subset of the class prior to graduation. In addition, the survey wa
s completed just prior to graduation by randomly selected students fro
m the class without the course. The average score increased from 29.2%
before to 85.5% after the course and 65.3% at graduation (p < 0.01).
The scores from the non-course class averaged 45.4%, and were signific
antly lower than scores of those who had taken the course (p < 0.001).
The course increased students' Knowledge and much was retained until
graduation. Non-course students learned only a small part of this info
rmation from other sources.