In a herd of 200 Spanish sheep, 20% of the animals developed unilatera
l or bilateral keratoconjunctivitis, affecting young and adult animals
. M. agalactiae was isolated from the conjunctival sac of 20 adult she
ep and three lambs, After a topical and parenteral treatment using tet
racycline and tylosine, all animals gradually recovered, One sheep was
sacrificed to carry out a pathological study of the cornea, where myc
oplasma were seen ultrastructurally. After 3 months of clinical presen
tation, M. agalactiae was again isolated from healthy sheep confirming
the persistence of this microorganism.