GALANIN - AN UNASSUMING NEUROPEPTIDE MOVES TO CENTER STAGE IN REPRODUCTION

Authors
CHEUNG CC CLIFTON DK STEINER RA
Citation
Cc. Cheung et al., GALANIN - AN UNASSUMING NEUROPEPTIDE MOVES TO CENTER STAGE IN REPRODUCTION, Trends in endocrinology and metabolism, 7(8), 1996, pp. 301-306
Citations number
50
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Trends in endocrinology and metabolism → ACNP
ISSN journal
10432760
Volume
7
Issue
8
Year of publication
1996
Pages
301 - 306
Database
ISI
SICI code
1043-2760(1996)7:8<301:G-AUNM>2.0.ZU;2-D
Abstract
Galanin is a neuropeptide widely distributed throughout the reproducti ve system including the brain, pituitary, testes, ovaries, and accesso ry reproductive tracts of both sexes. Within the hypothalamus, a subse t of GnRH-producing neurons also synthesizes galanin. Galanin gene exp ression in these GnRH neurons is highly inducible by estrogen. Galanin is thought to play an important role in the generation of the preovul atory LH surge, and may serve other functions yet to be discovered. (C ) 1996, Elsevier Science Inc.