FOOD-DEPENDENT CUSHINGS-DISEASE

We report a clinical case of a patient with corticotropin dependent Cu shing disease. In this patient ingestion of mixed meals is followed by an increase of ACTH and cortisol. This effects seems secondary to ing estion of proteins, and it can be reproduced by intravenous injection of aminoacids. The pattern observed is similar to what is observed in normal subjects. Neurotransmitter substrate from protein meals or afte r intravenous injection of aminoacids may influence the factors contro lling ACTH secretion in the studied patient.