CRYSTALS OF LIGAND-FREE BOVINE NEUROPHYSIN-II

Authors
WU CK ROSE JP ZHENG CS BRESLOW E WANG BC
Citation
Ck. Wu et al., CRYSTALS OF LIGAND-FREE BOVINE NEUROPHYSIN-II, Acta crystallographica. Section D, Biological crystallography, 52, 1996, pp. 946-949
Citations number
36
Categorie Soggetti
Crystallography,"Biochemical Research Methods",Biology
Journal title
Acta crystallographica. Section D, Biological crystallography → ACNP
ISSN journal
09074449
Volume
52
Year of publication
1996
Part
5
Pages
946 - 949
Database
ISI
SICI code
0907-4449(1996)52:<946:COLBN>2.0.ZU;2-M
Abstract
A modified neurophysin, des 1-6 bovine neurophysin II, has been crysta llized in the absence of bound hormone or hormone analogue. These crys tals represent the first crystals of ligand-free neurophysin, and are essential for understanding neurophysin-hormone recognition as well as hormone-induced neurophysin dimerization. The crystals diffract to be yond 1.8 Angstrom resolution, belong to space group P3(1)21 (or P3(2)2 1) with n = 48.85, c = 78.61 Angstrom, and contain one molecule per as ymmetric unit.