D. Nathwani et al., IMPACT OF AN INFECTION CONSULTATION SERVICE FOR BACTEREMIA ON CLINICAL MANAGEMENT AND USE OF RESOURCES, Quarterly Journal of Medicine, 89(10), 1996, pp. 789-797
Since 1993, the infection consultation service for bacteraemia has see
n 310 patients in the Medical and Surgical Directorates at Ninewells H
ospital and Kings Cross Hospital. A random sample of 100 was audited.
Case-notes were incomplete for five patients, leaving 95 fully-audited
patients. Clinical outcome measures were death from infection, and re
admission within 2 weeks of discharge. Initial treatment was inconsist
ent with antibiotic policy in 46 patients (48%). Antibiotic treatment
was changed in 37 (80%) of these patients: increased in intensity in 1
9 (41%) and decreased in 18 (39%). Changes were also made in 30 (61%)
of the 49 patients whose initial treatment was consistent with sepsis
policy-increased in seven (14%) and decreased in 23 (47%). Median dail
y antibiotic costs were lowered in patients whose initial treatment wa
s consistent with sepsis policy (pound 10.10 vs. pound 7.28, p=0.0274)
. However, in the other patients, savings were balanced by increases (
p=0.7696). Consultation required one consultant session per week (3.5
h) and the audit required an additional 16 consultant sessions. Seven
patients died, but only one death was directly related to infection. S
ix patients were readmitted to hospital within 2 weeks, in three due t
o recurrence of infection. Changes to treatment were recommended in th
e majority of patients, regardless of whether initial treatment compli
ed with the sepsis policy. The service primarily redistributed resourc
es rather than reducing costs. A fully audited service requires consid
erable consultant time, but we believe such time is well spent.