Jh. Greenberg et M. Katz, TREATMENT OF ANDROGENETIC ALOPECIA WITH A 7.5-PERCENT HERBAL PREPARATION, Journal of dermatological treatment, 7(3), 1996, pp. 159-162
A standardized 7.5% herbal extract preparation used to increase the de
nsity of hair growth was subjected to scientific investigation to evau
late its hair growth-promoting properties. A group of 24 healthy male
subjects under the age of 55 years with stage III-IV androgenetic alop
ecia were enrolled in a randomized double-blind parallel-group vehicle
-controlled study lasting 48 weeks. The hair inside a l-cm tattooed tr
iangle was harvested bimonthly. Measurements included total hair count
s, non-vellus hair counts, average hair length and total hair weight.
After 40 weeks of treatment, the mean total hair count increased by 77
% in the active group compared to a 3% increase in the placebo group (
P = 0.003). The number of non-vellus hairs in a 0.433 cm(2) area incre
ased by 169% for the active group compared to 33% for the placebo grou
p (P = 0.01). In the active group, 90% of the subjects showed an incre
ase of more than 35% in non-vellus hair count compared with only 33% o
f the placebo group (P < 0.05), and 60% of the active group had excell
ent results (> 100% increase in non-vellus hair count) compared with o
nly 8% of the placebo group (P < 0.05). It was seen that the standardi
zed herbal preparation was significantly more effective than the place
bo.