STUDIES OF SUCCINATE-DEHYDROGENASE INHIBITION (SDI) TEST WITH CISPLATIN ENCAPSULATED LIPOSOME AGAINST CANCER-CELLS

In the present study, by means of encapsulating into liposome, cisplat in was made a soluble capsule, and augmentation of the antitumor effec t through the cell affinity of liposome was investigated by chemosensi tivity test for cancer cells. Augmentation of the antitumor effect by collaboration of the cell affinity of liposome with the diffusion by c oncentration gradient was expected. However, although a difference in absorbancy was in fact observed, no statistically significant differen ce of effect superior to cisplatin alone was observed.