Since 1990 Endosteal implants have been inserted in the irradiated low
er jaw at our clinic, IMZ implants have been used for dental rehabilit
ation in 26 patients (21 male, 5 female) suffering from squamous cell
carcinomas stage T2-T4136, The implants were either placed in local bo
ne and soft tissue (group 1, n=60 implants), or in local bone after ma
rginal mandibulectomy and transplanted soft tissue (group 2, n=26 impl
ants), or in transplanted bone and soft tissue (group 3, n=52 implants
), Life-table analysis according to Kaplan-Meier demonstrated a 3-year
implant survival rate of 87.8% in Group 1, 69.1% in Group 2 and 58.3%
in Group 3, There was no statistical significant difference in the am
ount of marginal bone loss and the degree of marginal infection betwee
n the three groups (P>0.29). Major complications: A mandibular fractur
e passing through an empty implant socket 8 months after implant loss
(Group 2) was caused by postradiation-osteonecrosis; implant removal a
nd bone resection was mandatory, The poor results of the bone graft gr
oup may be explained by two patients, in whom simultaneous placement o
f implants in nonvascularized bone grafts was carried out, intraoral t
issue breakdown led to graft failure and loss of the implants (n=10).