T. Emori et al., POLYMORPHIC VENTRICULAR-TACHYCARDIA INDUCED BY INTRACORONARY INJECTION OF IOXAGLATE IN A PATIENT WITH BORDERLINE QT PROLONGATION, Journal of cardiovascular electrophysiology, 7(10), 1996, pp. 962-966
A 68-year-old female patient with borderline QT prolongation developed
polymorphic ventricular tachycardia soon after intracoronary injectio
n of ioxaglate, There was no coronary stenosis or vasospasm, To invest
igate abnormality of the ventricular repolarization, we recorded the m
onophasic action potential (MAP) during coronary angiography, Ioxaglat
e prolonged the MAP duration regionally in the perfused area and produ
ced temporal dispersion of ventricular repolarization.