The proportion of women infected with the human immunodeficiency virus
(HIV) continues to increase. Over one-half of women acquire the virus
through heterosexual contact. The diagnoses that define the acquired
immunodeficiency syndrome and the use of antiretroviral therapy are si
milar in men and women, except in pregnancy. However, management decis
ions differ significantly regarding contraceptive and gynecologic care
. Besides abstinence, use of the latex condom continues to be the most
effective way of preventing transmission of HIV. The management of hu
man papillomavirus-associated disease, pelvic inflammatory disease and
vaginal candidiasis is especially challenging in women with HIV infec
tion. A positive status for the virus does not appear to affect pregna
ncy outcome. Each year, up to 2,000 infants are born infected with HIV
. Transmission can occur by transplacental or intrapartum spread or th
rough breast milk. Since 1994, prophylaxis with zidovudine has been sh
own to be an effective method of limiting transmission to infants. It
is important to offer all pregnant women a test for HIV, with counseli
ng provided both before and after the test, even if testing does not b
ecome mandatory under the law.