NONOCCLUSIVE MESENTERIC INFARCTION IN CONTINUOUS AMBULATORY PERITONEAL-DIALYSIS

Nonocclusive mesenteric infarction has recently been diagnosed with in creasing frequency in dialysis patients. Although most reports have co ncerned patients on hemodialysis, the condition has also been reported to occur in patients on continuous ambulatory peritoneal dialysis. Th is report describes such a case developing in a woman whose end-stage renal failure was due to adult polycystic kidney disease. Associated p redisposing factors were the presence of orthostatic hypoxemia, postur al hypotension and extensive atheromatous changes of the abdominal aor ta. In keeping with the known difficulty of establishing the diagnosis of mesenteric ischemia, the diagnosis in our patient was also delayed . She was initially thought to suffer from an episode of peritonitis a nd/or colonic perforation secondary to the performance of a cleansing enema. Only upon showing pneumatosis coli of the right colon on abdomi nal computerized tomography was the correct diagnosis made. Laparotomy revealed extensive necrosis of the ascending and transverse colon. A total colectomy and ileorectal anastomosis were performed. The patient died on the 17th day following surgery. This case serves to illustrat e that mesenteric infarction should be considered in predisposed patie nts on continuous ambulatory peritoneal dialysis. The presence of peri tonitis may mask the underlying pathology and waylay the unwary physic ian.