Objective: To quantify the frequency of blood loss necessitating trans
fusion and identify the clinical factors predictive of severe hemorrha
ge in children with femoral fractures. Design: Retrospective review of
computerized discharge diagnoses and medical records between January
1, 1987, and July 31, 1992. Setting: Tertiary care children's hospital
. Patients: Children younger than 18 years of age, discharged between
January 1, 1987, and July 31, 1992, with a final diagnosis of femur fr
acture. Results: The 257 patients ranged in age from birth to 18 years
with a mean of 6.5 years; 183 (71%) were male. Fractures were closed
in 250 (98%) and represented isolated injuries in 225 (87%) patients.
The mean systolic blood pressure (SBP) was 119 mmHg, the mean heart ra
te (HR) was 114 beats/min, and the mean hematocrit (Hct) was 35.2% on
arrival. Eight (2.9%) patients had a SBP less than 90 mmHg, all of whi
ch were normal values for age. There were 19 patients with a HR, >150,
all were <4 years old with a mean SBP of 110 mmHg and a mean Hct of 3
5.6%; none required transfusion. There were 18 patients with a Hct <30
%, 4/18 or 22% required transfusion. Seven of the 257 patients (2.7%)
received blood transfusions. All were male, with closed fractures, who
were older (11.7 +/- 4.9 vs 6.3 +/- 4.7 years) than the 250 nontransf
used patients (P = 0.004). There were no significant differences in pr
esenting vital signs, Hct, type of fracture, or time required to get t
o the emergency department. Five of the seven transfused patients pres
ented with a Hct <30% as compared to 13 of the 250 nontransfused patie
nts (P < 0.00002). Two of the transfused patients had isolated femoral
fractures; one with hemophilia and the other with a prior femoral fra
cture. The remaining five patients were multiple trauma victims, with
significant injuries in addition to femoral fractures. Conclusions: Ot
herwise healthy pediatric patients with isolated femoral fractures rar
ely lose sufficient amounts of blood to necessitate blood transfusion.
The majority may be managed by observation alone. Multiple trauma (mu
ltiple fractures, pelvic disruptions, retroperitoneal injuries) and un
derlying disorders are indications for careful monitoring, Hct determi
nation, and cross match for blood. Patients who are older, present wit
h a Hct <30%, or who have multiple traumatic injuries have a relativel
y greater risk of needing a transfusion.