AZASUGAR GLYCOSIDASE INHIBITORS - USEFUL TOOLS FOR GLYCOBIOLOGISTS

Authors
Citation
S. Picasso, AZASUGAR GLYCOSIDASE INHIBITORS - USEFUL TOOLS FOR GLYCOBIOLOGISTS, Chimia, 50(12), 1996, pp. 648-649
Citations number
6
Categorie Soggetti
Chemistry
Journal title
ChimiaACNP
ISSN journal
00094293
Volume
50
Issue
12
Year of publication
1996
Pages
648 - 649
Database
ISI
SICI code
0009-4293(1996)50:12<648:AGI-UT>2.0.ZU;2-G
Abstract
Glycosidase inhibitors are moving increasingly as potential agents for the treatment of diseases by altering glycosylation or catabolism of glycoconjugates. The azasugars, a potent class of inhibitors have rece ived much attention as tools for therapeutic investigation and in unde rstanding of certain biological processes such as glycoprotein process ing and enzymatic mechanisms. In this paper, We present some new synth etic azasugar compounds which show interesting activity as glycosidase inhibitors.