RUMINANT CLUSTER WC13

Five monoclonal antibodies (mAbs) belonged to preliminary cluster 27; however, only two mAbs, Buf13 (3W-506) and Co-3D1D4(3W-202), were show n to detect the same surface antigen and belong to WC13. The other thr ee mAbs, IVA120 (3W-323), IVA197 (3W-533) and IVA198 (3W-290), detecte d a 45 kDa molecule that could be fibrinogen (Mateo A., Perez de la La stra, J., Moreno, A., Dusinsky, R., Bilka, F., Simon, M., Horovska, L. , Naessens, J. and Llanes, D., 1996. Biochemical characterization of a ntigens detected with anti-platelet monoclonal antibodies. Vet. Immuno l. Immunopathol., 52: 363-370; Perez de la Lastra, J.M., Mateo, Dusins ky, R., Bilka, Simon, M., Horovska, L. and Llanes, D., 1996. Two monoc lonal antibodies from the platelet panel recognize sheep plasma fibron igen. Vet. Immunol. Immunopathol., 52:).