2 MONOCLONAL-ANTIBODIES FROM THE PLATELET PANEL RECOGNIZE SHEEP PLASMA-FIBRINOGEN

Authors
DELALASTRA JMP MATEO A DUSINSKY R SIMON M LLANES D
Citation
Jmp. Delalastra et al., 2 MONOCLONAL-ANTIBODIES FROM THE PLATELET PANEL RECOGNIZE SHEEP PLASMA-FIBRINOGEN, Veterinary immunology and immunopathology, 52(4), 1996, pp. 371-375
Citations number
8
Categorie Soggetti
Immunology,"Veterinary Sciences
Journal title
Veterinary immunology and immunopathology → ACNP
ISSN journal
01652427
Volume
52
Issue
4
Year of publication
1996
Pages
371 - 375
Database
ISI
SICI code
0165-2427(1996)52:4<371:2MFTPP>2.0.ZU;2-H
Abstract
Among the monoclonal antibodies (mAbs) submitted to the third Workshop , two mAbs, IVA120 (3W-323) and IVA198 (3W-290), could be identified t o recognize the sheep fibrinogen molecule. The apparent molecular weig ht of the immunoprecipitated 48-60kDa cell surface protein under reduc ing conditions suggested this antigen could be the fibrinogen molecule . ELISA and immunoblotting assays, performed with commercially availab le sheep plasma fibrinogen, confirmed that these two mAbs recognize tw o different epitopes present on the sheep fibrinogen molecule.