Ultrasonographically-guided core biopsy has been used as an adjunct to
triple assessment when fine-needle aspiration cytology was inadequate
or equivocal, if the overall assessment of the patient was uncertain,
or if it was deemed the preferred diagnostic option. Some 143 of 2603
patients had a guided core biopsy, 125 to establish the diagnosis adn
18 to obtain histology in cytologically proven malignancy. A diagnosi
s of malignancy was established in 43 of the 125 patients who had a di
agnostic core biopsy. Some 45 patients with benign disease were either
discharged or returned to follow-up on the basis of the core biopsy.
The remaining 37 patients required surgical biopsy, of whom 13 had mal
ignant and 24 benign disease. The overall positive predictive value fo
r malignancy was 98 per cent. Experience with ultrasonographically-gui
ded core biopsy shows that it can reduce the need for surgical biopsy
in both benign and malignant conditions of the breast.