THE EFFECT OF LITHIUM IODIDE ON THE ACID-PROMOTED CYCLIZATION OF 4-[(1-INDOLYLCARBONYL)METHYL]-1,4-DIHYDROPYRIDINES

Authors
BENNASAR ML JIMENEZ JM SUFI BA BOSCH J
Citation
Ml. Bennasar et al., THE EFFECT OF LITHIUM IODIDE ON THE ACID-PROMOTED CYCLIZATION OF 4-[(1-INDOLYLCARBONYL)METHYL]-1,4-DIHYDROPYRIDINES, Tetrahedron letters, 37(42), 1996, pp. 7653-7656
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
42
Year of publication
1996
Pages
7653 - 7656
Database
ISI
SICI code
0040-4039(1996)37:42<7653:TEOLIO>2.0.ZU;2-P
Abstract
1,4-Dihydropyridines 3 resulting from the addition of the enolate deri ved from 1-acetylindole (1) to pyridinium salts 2 do not undergo cycli zation under the usual acidic conditions, but do satisfactorily cycliz e to the tetracyclic derivatives 4 by treatment with TsOH in the prese nce of lithium iodide. Copyright (C) 1996 Elsevier Science Ltd