Gn. Smith et al., THE SONOGRAPHIC FINDING OF PERSISTENT UMBILICAL-CORD CYSTIC MASSES ISASSOCIATED WITH LETHAL ANEUPLOIDY AND OR CONGENITAL-ANOMALIES/, Prenatal diagnosis, 16(12), 1996, pp. 1141-1147
Advancements in sonographic technology have led to improved prenatal d
etection of fetal anomalies. Umbilical cord cystic masses are being de
tected prenatally and several case reports have appeared in the litera
ture. We report three new cases in which umbilical cord cystic masses
were detected prenatally; two cases in the later half of pregnancy and
one case in the first trimester. The literature was reviewed and summ
aries of the 23 reported cases of persistent second- and third-trimest
er umbilical cord cystic masses and their implications are discussed.
There is a high association (18 of 23 cases) with lethal chromosomal a
nomalies and/or congenital malformations suggesting that the finding o
f an isolated umbilical cord cystic mass should lead to further detail
ed sonographic evaluation.