I(18Q) IN AMNIOTIC AND FETAL CELLS WITH A NORMAL KARYOTYPE IN DIRECT CHORIONIC VILLUS SAMPLING - CYTOGENETICS AND PATHOLOGY

Authors
LEVYMOZZICONACCI A PIQUET C SCHEINER C ADRAI J POTIER A PELISSIER MC PHILIP N
Citation
A. Levymozziconacci et al., I(18Q) IN AMNIOTIC AND FETAL CELLS WITH A NORMAL KARYOTYPE IN DIRECT CHORIONIC VILLUS SAMPLING - CYTOGENETICS AND PATHOLOGY, Prenatal diagnosis, 16(12), 1996, pp. 1156-1159
Citations number
21
Categorie Soggetti
Obsetric & Gynecology
Journal title
Prenatal diagnosis → ACNP
ISSN journal
01973851
Volume
16
Issue
12
Year of publication
1996
Pages
1156 - 1159
Database
ISI
SICI code
0197-3851(1996)16:12<1156:IIAAFC>2.0.ZU;2-Y
Abstract
A case of false-negative discrepancy between results of chorionic vill i (direct preparation) and those of fetal tissue with an isochromosome 18q [i(18q)] in amniotic cells and fetal blood is reported. Fluoresce nce in situ hybridization (FISH) confirmed this uncommon chromosomal r earrangement. The fetus showed cyclopia and multiple congenital anomal ies which have never been reported in cases of i(18q).