The increased incidence of cerebral toxoplasmosis in AIDS has led to a
resurgence in the use of sulphadiazine. One complication of this is a
cute renal failure secondary to sulphadiazine-induced crystalluria. Th
ree cases are described which demonstrate a spectrum of ultrasound fin
dings ranging from echogenic foci in the renal parenchyma to echogenic
material in both dilated and non-dilated collecting systems. In patie
nts with AIDS having sulphadiazine treatment, these ultrasonic finding
s suggest that sulphadiazine is the cause of the renal failure.