Background.-Although migraine headaches affect a large segment of the
population, no objective measure of therapeutic success is currently a
vailable. Comparing visit frequency and associated costs of cars befor
e and after introduction of a new therapy represents an important surr
ogate measure of success. Methods.-One hundred four patients regularly
attending a headache clinic for migraines at a tertiary care hospital
were instructed in the use of a new abortive migraine therapy. Medica
l appointment and financial systems were searched retrospectively for
visit frequency and associated patient care and institutional costs. T
he number of visits and mean costs 18 months before and after initiati
on of therapy were compared using the signed rank test and paired t-te
st, respectively. Results.-The median number of visits made by study s
ubjects to the headache clinic fell significantly following sumatripta
n test dosing (P<0.001). Prior to the new treatment, mean total patien
t care and institutional costs were $228.59 and $112.81 per person, re
spectively, and fall to $135.93 and $78.16 (P<0.001) after therapy beg
an. Conclusions.-These data suggest that many patients with migraine b
enefit from sumatriptan, seek medical attention in a headache clinic l
ess often, and incur fewer costs following initiation of treatment wit
h this drug.