AMINO-ACIDS AND PEPTIDES .47. FACILE SYNTHESIS OF FLAVACOL, DEOXYMUTA-ASPERGILLIC ACID AND OPTICALLY-ACTIVE DEOXYASPERGILLIC ACID FROM DIPEPTIDYL ALDEHYDES

Authors
OKADA Y TAGUCHI H YOKOI T
Citation
Y. Okada et al., AMINO-ACIDS AND PEPTIDES .47. FACILE SYNTHESIS OF FLAVACOL, DEOXYMUTA-ASPERGILLIC ACID AND OPTICALLY-ACTIVE DEOXYASPERGILLIC ACID FROM DIPEPTIDYL ALDEHYDES, Chemical and Pharmaceutical Bulletin, 44(12), 1996, pp. 2259-2262
Citations number
23
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
44
Issue
12
Year of publication
1996
Pages
2259 - 2262
Database
ISI
SICI code
0009-2363(1996)44:12<2259:AAP.FS>2.0.ZU;2-V
Abstract
2(1H)-Pyrazinone ring-containing natural products, flavacol, deoxymuta -aspergillic acid and finally optically active deoxyaspergillic acid, were easily synthesized by a newly developed procedure for preparation of 2(1H)-pyrazinone derivatives from dipeptidyl aldehyde hydrochlorid es, The absolute configuration of natural deoxyaspergillic acid was sy nthetically determined as S.