A. Klovning et al., VALIDITY OF A SCORED UROLOGICAL HISTORY IN DETECTING DETRUSOR INSTABILITY IN FEMALE URINARY-INCONTINENCE, Acta obstetricia et gynecologica Scandinavica, 75(10), 1996, pp. 941-945
Background. Kauppila and co-workers published in 1982 a detrusor insta
bility score (DIS) for women with urinary incontinence. The aim of thi
s study was to determine the validity of the DIS in an outpatient clin
ic for urogynecology. Methods. The DIS questionnaire was incorporated
as part of an independent history at the first consultation. The DIS w
as compared with clinical diagnosis in 250 patients consecutively refe
rred for evaluation. Sensitivity, specificity, positive predictive val
ue (PPV), negative predictive value (NPV) and overall accuracy of the
DIS in diagnosing genuine stress incontinence (GSI) were calculated us
ing the gynecologist's clinical diagnosis based on urodynamic findings
as the gold standard. An ROC-curve was constructed for determining th
e optimum cut-off point for the DIS for women with GSI. Results. A cut
-off point at 7 for the DIS, yielded sensitivity=0.77, specificity=0.5
2, PPV=0.74, NPV=0.52 and an overall accuracy=0.68. Optimum cut-off po
int for GSI according to the ROC-curve was at a DIS-value of 5, yieldi
ng sensitivity=0.60, specificity=0.77, PPV=0.82, NPV=0.52 and overall
accuracy=0.66. Conclusions. A cut-off point at 7 diagnosed 159 women (
64%) as having GSI, 41 of them (16% of 250) having a false positive DI
S. Similarly a cut-off point at 5 diagnosed 112 women (45%) as having
GSI, 20 of them (8% of 250) having a false positive DIS. These women,
if otherwise feasible and indicated, might perhaps undergo continence
surgery without preoperative urodynamics. A lower cut-off point than o
riginally proposed ought therefore to be used if the DIS is to become
a useful preoperative tool for this kind of surgery.